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Company · patent cliff and acquisitions

AbbVie’s patent cliff

The 3 drugs tracked here made $28.7B of AbbVie’s 2025 revenue (47%) and lose US exclusivity by 2037. Since 2023, AbbVie has closed 5 acquisitions of $1B or more, worth $33.2B in total.

Losing US exclusivity by 2030
NoneFirst tracked loss is 2032
By 2037
$28.7B47% of $61.2B
Acquisitions since 2023
$33.2B5 deals of $1B or more
Bought with an approved product
1 of 5ImmunoGen

2025 revenue losing US exclusivity, by year

2031–2037
0%25%50%75%100%
2032
4.7%$2.9B · Imbruvica
2033
29%$17.6B · Skyrizi
2037
14%$8.3B · Rinvoq

Bars are each drug's 2025 sales as a share of AbbVie’s total revenue ($61.2B). Only drugs tracked here are counted, so full exposure can be higher. Tap a bar for the drug's page.

Acquisitions since 2023

ClosedCompany boughtValueAreaWhat it broughtAt closing
Feb 2024 ImmunoGenAbbVie, November 2023 · AbbVie, February 2024 $10.1B Oncology Elahere, an antibody-drug conjugate for ovarian cancer Approved product
Aug 2024 Cerevel TherapeuticsAbbVie, December 2023 · AbbVie, August 2024 $8.7B Neuroscience Tavapadon for Parkinson's disease (Phase 3) and emraclidine for schizophrenia Pipeline only
Dec 2024 Aliada TherapeuticsAbbVie, October 2024 $1.4B Neuroscience ALIA-1758, an early antibody for Alzheimer's disease Pipeline only
Aug 2025 Capstan TherapeuticsAbbVie, June 2025 · AbbVie 10-K 2025 $2.1B Immunology CPTX2309, an early in vivo CAR-T therapy for autoimmune disease Pipeline only
Sep 2026 Apogee TherapeuticsAbbVie, June 2026 · AbbVie, September 2026 $10.9B Immunology Zumilokibart, a long-acting IL-13 antibody for atopic dermatitis, and asthma programs Pipeline only
5 deals$33.2B

Acquisitions of whole companies worth $1B or more, announced since January 2023. Values are the headline price AbbVie announced, excluding milestone payments unless noted. Licensing deals are not included.

Losing vs buying, by area

AreaAt risk by 2037Acquisitions since 2023
Immunology$25.9B$13.0B
Oncology$2.9B$10.1B
Neuroscience–$10.1B

Immunology is where AbbVie has the most revenue at risk and where it has spent the most on acquisitions. At risk is 2025 sales of tracked drugs losing US exclusivity by 2037; acquisitions are the headline value of deals closed since 2023.

How to read this

The two figures measure different things. Revenue at risk is what the drugs earned in 2025. A deal's value is what AbbVie paid, not the sales it will bring in. Only one of the 5 companies it bought was already selling an approved product at closing (ImmunoGen); the rest brought pipeline drugs whose sales are years away and may never arrive. So this page shows the two side by side rather than claiming how much of the gap the deals fill.

What changed for AbbVie

  1. Acquisition
    AbbVie completes its $10.9B Apogee acquisition

    The deal adds zumilokibart, a long-acting antibody in development for atopic dermatitis. It is AbbVie's largest acquisition since 2023. AbbVie

  2. Date pushed back · 2032 → 2037
    Settlements push Rinvoq's US generic entry to April 2037

    AbbVie settled with every generic filer. Analysts had modeled US exclusivity ending in 2032. Fierce Pharma

Other companies

Sources

Revenue: AbbVie FY2025. Drug sales and dates are sourced on each drug's page; each deal links to AbbVie’s announcement or filing in the table above.

See all 45 drugs on the patent cliff →