Pharma Patent Cliffby readouts.io
Late-stage pipeline · Vaccine

Late-stage vaccine biotechs

$11.7B of 2025 vaccine blockbuster sales lose US exclusivity by 2037, led by Prevnar 20, Gardasil. These 1 public biotech have 2 vaccine treatments in Phase 3 or filed with the FDA, 1 of them already filed.

Who is losing vaccine revenue

2025 sales each company reports from tracked vaccine treatments losing US exclusivity by 2037. Big pharma has spent $3.35B on 2 vaccine acquisitions since 2023. See the deals →

1 biotechs with late-stage vaccine treatments

Vaxcyte PCVX

VAX-31's 31-valent pneumococcal vaccine thesis hinges on Phase 3 non-inferiority and superiority data against Prevnar 20 and Capvaxive

  • VAX-31 FiledPneumonia · Pneumococcal conjugate vaccine
  • VAX-31 Phase 3Invasive Pneumococcal Disease · Pneumococcal conjugate vaccine
Read the thesis on Readouts →

Filed treatments are listed first. This shows where late-stage treatments are being developed, not which companies will be acquired. Pipeline data and summaries from Readouts as of 29 September 2026; companies already acquired are left out.

Other areas: Oncology · Immunology · Cardiometabolic · Infectious disease · Neuroscience · Other areas